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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 12
2003 10
2004 11
2005 13
2006 13
2007 6
2008 11
2009 11
2010 8
2011 13
2012 11
2013 6
2014 12
2015 8
2016 9
2017 5
2018 2
2019 5
2020 4
2021 6
2022 8
2023 8
2024 3

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178 results

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Page 1
The central role of DNA damage in the ageing process.
Schumacher B, Pothof J, Vijg J, Hoeijmakers JHJ. Schumacher B, et al. Among authors: hoeijmakers jhj. Nature. 2021 Apr;592(7856):695-703. doi: 10.1038/s41586-021-03307-7. Epub 2021 Apr 28. Nature. 2021. PMID: 33911272 Free PMC article. Review.
DNA damage, aging, and cancer.
Hoeijmakers JH. Hoeijmakers JH. N Engl J Med. 2009 Oct 8;361(15):1475-85. doi: 10.1056/NEJMra0804615. N Engl J Med. 2009. PMID: 19812404 Review. No abstract available.
Cellular senescence drives age-dependent hepatic steatosis.
Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Grellscheid SN, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D. Ogrodnik M, et al. Among authors: hoeijmakers jhj. Nat Commun. 2017 Jun 13;8:15691. doi: 10.1038/ncomms15691. Nat Commun. 2017. PMID: 28608850 Free PMC article.
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ. Baar MP, et al. Among authors: hoeijmakers jhj. Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031. Cell. 2017. PMID: 28340339 Free PMC article.
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Demaria M, Ohtani N, Youssef SA, Rodier F, Toussaint W, Mitchell JR, Laberge RM, Vijg J, Van Steeg H, Dollé ME, Hoeijmakers JH, de Bruin A, Hara E, Campisi J. Demaria M, et al. Among authors: hoeijmakers jh. Dev Cell. 2014 Dec 22;31(6):722-33. doi: 10.1016/j.devcel.2014.11.012. Epub 2014 Dec 11. Dev Cell. 2014. PMID: 25499914 Free PMC article.
Genome-wide RNA polymerase stalling shapes the transcriptome during aging.
Gyenis A, Chang J, Demmers JJPG, Bruens ST, Barnhoorn S, Brandt RMC, Baar MP, Raseta M, Derks KWJ, Hoeijmakers JHJ, Pothof J. Gyenis A, et al. Among authors: hoeijmakers jhj. Nat Genet. 2023 Feb;55(2):268-279. doi: 10.1038/s41588-022-01279-6. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658433 Free PMC article.
Nuclear Genomic Instability and Aging.
Niedernhofer LJ, Gurkar AU, Wang Y, Vijg J, Hoeijmakers JHJ, Robbins PD. Niedernhofer LJ, et al. Among authors: hoeijmakers jhj. Annu Rev Biochem. 2018 Jun 20;87:295-322. doi: 10.1146/annurev-biochem-062917-012239. Annu Rev Biochem. 2018. PMID: 29925262 Review.
MARK-AGE biomarkers of ageing.
Bürkle A, Moreno-Villanueva M, Bernhard J, Blasco M, Zondag G, Hoeijmakers JH, Toussaint O, Grubeck-Loebenstein B, Mocchegiani E, Collino S, Gonos ES, Sikora E, Gradinaru D, Dollé M, Salmon M, Kristensen P, Griffiths HR, Libert C, Grune T, Breusing N, Simm A, Franceschi C, Capri M, Talbot D, Caiafa P, Friguet B, Slagboom PE, Hervonen A, Hurme M, Aspinall R. Bürkle A, et al. Among authors: hoeijmakers jh. Mech Ageing Dev. 2015 Nov;151:2-12. doi: 10.1016/j.mad.2015.03.006. Epub 2015 Mar 24. Mech Ageing Dev. 2015. PMID: 25818235 Free article. Review.
The DNA damage response to transcription stress.
Lans H, Hoeijmakers JHJ, Vermeulen W, Marteijn JA. Lans H, et al. Among authors: hoeijmakers jhj. Nat Rev Mol Cell Biol. 2019 Dec;20(12):766-784. doi: 10.1038/s41580-019-0169-4. Epub 2019 Sep 26. Nat Rev Mol Cell Biol. 2019. PMID: 31558824 Review.
178 results